By F. Bandello, M. Battaglia Parodi, A.J. Augustin, P. Iacono, R.O. Schlingemann, U. Schmidt-Erfurth, F.D. Verbraak
The advance of treatment with anti-angiogenics or vascular endothelial progress issue inhibitors (anti-VEGF) has marked the start of a brand new period in neovascularization and macular edema therapy. Its major targets are the inhibition of development and improvement of latest vessels besides the aid of vascular permeability. the benefits over traditional laser photocoagulation are obtrusive as laser remedy regularly leaves scars and factors a retinal sensitivity deterioration. beginning with an overview of therapy rules, this quantity covers all facets of anti-VEGF remedy for ophthalmological issues. specifically, particular chapters are devoted to age-related macular degeneration, degenerative myopia, angioid streaks, inflammatory illnesses, hereditary dystrophies, retinal vein occlusion, diabetic retinopathy, ocular tumors, in addition to anterior section neovascularization. The publication supplies an replace at the program of anti-VEGF in ocular illnesses to basic ophthalmologists in addition to retina experts.
Read Online or Download Anti-vegf (Developments in Ophthalmology) PDF
Best ophthalmology books
Edited by means of and that includes contributions from world-class researchers, Ophthalmological Imaging and functions deals a unified paintings of the newest human eye imaging and modeling suggestions which were proposed and utilized to the prognosis of ophthalmologic difficulties, together with irritation, cataracts, diabetic retinopathy, and glaucoma.
With the swift development of corneal topography and wavefront applied sciences and the elevated program of corneal topography not just in refractive but additionally in top rate IOL surgical procedure, a brand new version of the best-selling Corneal Topography: A advisor for scientific program within the Wavefront period could be the most efficient source for either ophthalmologists and optometrists.
Stereo Atlas of Fluorescein and Indocyanine eco-friendly Angiography is a 3-dimensional visible survey of ophthalmic angiography circumstances followed through diagnostic details. it's an easy-to-use education instrument to assist practitioners and citizens higher diagnose and deal with ocular stipulations.
This well-illustrated e-book is meant because the go-to consultant for the identity and administration of the issues linked to particular glaucoma approaches. all the regularly played tactics are lined: filtration surgical procedure, together with trabeculectomy and exhibit shunt, nonpenetrating surgical procedures comparable to deep sclerectomy and canaloplasty, techniques regarding the location of tube shunt units, glaucoma laser remedies, and minimally invasive glaucoma surgical procedures (MIGS).
- New Viewpoints on the Origin of Squint: A Clinical and Statistical Study on its Nature, Cause and Therapy
- Scleritis (Fundamentals in Clinical Ophthalmology)
- Handbook of Neuroimaging for the Ophthalmologist
- Candidacy for Implantable Hearing Devices: Candidacy for Implantable Hearing Devices (Audiology and Neuro-Otology)
- Shields Textbook of Glaucoma (Allingham, Shields' Textbook of Glaucoma)
Extra info for Anti-vegf (Developments in Ophthalmology)
Clin Colorectal Cancer 2003;3:85–88. 33 Kabbinavar F, Hurwitz HI, Fehrenbacher L, et al: Phase II, randomized trial comparing bevacizumab plus fluorouracil (FU)/leucovorin (LV) with FU/LV alone in patients with metastatic colorectal cancer. J Clin Oncol 2003;21:60–65. 34 Hurwitz H, Fehrenbacher L, Novotny W, et al: Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. N Engl J Med 2004;350:2335–2342. 35 Mordenti J, Cuthbertson RA, Ferrara N, et al: Comparisons of the intraocular tissue distribution, pharmacokinetics, and safety of 125I-labeled fulllength and Fab antibodies in rhesus monkeys following intravitreal administration.
51] included 81 eyes of 79 patients receiving intravitreal bevacizumab on a monthly basis until resolution of macular edema, subretinal fluid or pigment epithelium detachment and revealed a median gain of 20 letters at 8 weeks. Mean retinal thickness of the central 1 mm was also statistically significantly decreased. Although intravitreal bevacizumab seems to be well tolerated in general according to the published data , there are several reports about serious ocular inflammation after intravitreal injection [53–57].
6 Reynolds R, Hartnett ME, Atkinson JP, et al: Plasma complement components and activation fragments: associations with age-related macular degeneration genotypes and phenotypes. Invest Ophthalmol Vis Sci 2009;50:5818–5827. 7 Morohoshi K, Goodwin AM, Ohbayashi M, Ono SJ: Autoimmunity in retinal degeneration: autoimmune retinopathy and age-related macular degeneration. J Autoimmun 2009;33:247–254. 34 8 Okemefuna AI, Nan R, Miller A, et al: Complement factor H binds at two independent sites to C-reactive protein in acute phase concentrations.
Anti-vegf (Developments in Ophthalmology) by F. Bandello, M. Battaglia Parodi, A.J. Augustin, P. Iacono, R.O. Schlingemann, U. Schmidt-Erfurth, F.D. Verbraak